Fort Lauderdale, Florida — Researchers might have found an answer to the puzzling and sometimes controversial problem of opioid-induced hyperalgesia (OIH). A new study shows that dexmedetomidine, a ...

February 5, 2010 (San Antonio, Texas) — Stimulation of the spinal cord is effective in treating secondary hyperalgesia and is worthy of further study, researchers reported here at the American Academy ...

Narcotics can treat pain, but may also circumvent the need to address its cause. And, while pain may be diminished, the ...

Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems - prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same ...

Researchers at the University of Alabama at Birmingham and Baylor College of Medicine, Houston, Texas, now have shown that blocking the activity of an enzyme called Tiam1 in certain spinal neurons ...

Sites of action of opioids for pain relief include the brain (cortex, thalamus, hypothalamus, locus coeruleus, amygdala, and periaqueductal gray matter), spinal cord, and peripheral-nerve membrane.

Pain is the most common reason for which people seek medical attention. Generally opioids are prescribed for the management of pain. However, chronic pain can persist or worsen despite aggressive ...

Pain responses are triggered in response to physical injury as well as psychological or emotional stressors. However, the mechanisms underlying social or emotional pain transmission are poorly ...

Research has shown that chronic sleep disruption (CSD) promotes pain, also known as hyperalgesia, which can commonly be experienced as headaches or body pain after a night of poor sleep. However, the ...