Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

For decades, Americans have been told a simple story about addiction: taking drugs damages the brain—and the earlier in life children start using substances, the more likely they are to progress ...

Methamphetamine doesn’t just spike levels of the pleasure-inducing hormone dopamine in the reward pathways of the brain – it also provokes damaging brain inflammation through similar mechanisms. Meth ...

Caron is evolving addiction treatment by combining neurorestorative care with emerging medical innovations that target the brain and support long-term recovery.

GLP-1 drugs, originally developed for diabetes and obesity, may also curb addictive behaviors by acting on reward circuits in the brain. Early trials show reductions in alcohol intake, opioid seeking, ...

A popular class of drugs for treating diabetes and obesity may reduce addiction, including abuse of alcohol, tobacco, cannabis, opioids and cocaine, according to research published March 4 by ...

A patient of mine, a veteran who had tried to quit smoking for over a decade, told me that after he started a GLP-1 drug for his diabetes, he lost interest in cigarettes. He didn’t use a patch. He ...